Just squirt under the toenail right on the fungus. This is a water-based product with no acid, it does contain alcohol, so avoid getting it into the eyes or mucous membranes. 4x was developed by a local chemist and has never been offered to the public before now. You've tried all the rest now try the best !!! (It is important to supplement your diet with Royal Jelly capsules; as it contains 10 HDA which helps to halt the harmful growth of bacterial, viral and fungal infections.